Formoterol Fumarate and Budesonide Inhalation 200 mcg (Budisure F 200) Third Party Manufacturing, Franchise Opportunity, Supplies and Exporters In India

Formoterol Fumarate and Budesonide Inhalation 200 mcg is a combination medication used in the management of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). This inhalation therapy combines two active ingredients: Formoterol Fumarate, a long-acting beta2-adrenergic agonist (LABA), and Budesonide, a corticosteroid. The combination of these two components offers both anti-inflammatory and bronchodilator effects, providing relief from symptoms and helping to prevent the worsening of respiratory conditions.

Uses of Formoterol Fumarate and Budesonide Inhalation

Formoterol Fumarate and Budesonide Inhalation are primarily used for the long-term management of asthma and COPD. It is not intended for the immediate relief of acute bronchospasm but is instead prescribed as a maintenance therapy to control and prevent symptoms such as wheezing, shortness of breath, chest tightness, and coughing. The dual-action approach of the medication targets inflammation and bronchoconstriction, making it a comprehensive solution for individuals with persistent respiratory symptoms.

In asthma management, this inhalation therapy is suitable for patients who require both an inhaled corticosteroid and a long-acting beta2-agonist. It is also used in COPD treatment, particularly in patients with frequent exacerbations despite the use of regular bronchodilators.

Indications of Formoterol Fumarate and Budesonide Inhalation

Formoterol Fumarate and Budesonide Inhalation is indicated for:

1. Asthma: As a maintenance treatment in patients with moderate to severe asthma who require both an inhaled corticosteroid and a long-acting beta2-agonist to control their symptoms. It is used in patients who experience frequent exacerbations and need more than just a rescue inhaler for symptom control.

2. Chronic Obstructive Pulmonary Disease (COPD): For the management of COPD, including chronic bronchitis and emphysema, in patients who experience frequent exacerbations despite using bronchodilators alone. It helps in reducing the frequency and severity of COPD exacerbations and improving lung function.

Benefits of Formoterol Fumarate and Budesonide Inhalation

The combination of Formoterol Fumarate and Budesonide offers several benefits:

1. Improved Symptom Control: The medication provides 24-hour control of asthma and COPD symptoms, reducing the frequency and severity of symptoms such as wheezing, coughing, and shortness of breath.

2. Dual Action: By combining a bronchodilator (Formoterol) with an anti-inflammatory agent (Budesonide), the medication addresses both the underlying inflammation and bronchoconstriction associated with asthma and COPD. This dual action ensures comprehensive management of respiratory conditions.

3. Reduced Exacerbations: Regular use of this combination inhaler has been shown to decrease the frequency of exacerbations in both asthma and COPD patients, leading to fewer hospitalizations and emergency room visits.

4. Enhanced Quality of Life: With better control of symptoms and fewer exacerbations, patients experience an improved quality of life, with less interference from their respiratory condition in daily activities.

Side Effects

Like all medications, Formoterol Fumarate and Budesonide Inhalation may cause side effects. Being aware of these possible effects is important, even if they don’t encounter everyone.

Common Side Effects:

1. Oral Thrush: Inhaled corticosteroids like Budesonide can cause a fungal infection in the mouth known as oral thrush (candidiasis). This is usually characterized by white patches in the mouth or throat and can be minimized by rinsing the mouth with water after using the inhaler.

2. Hoarseness: Some patients may experience a change in voice or hoarseness as a result of the corticosteroid component.

3. Tremors: Formoterol, being a beta2-agonist, may cause tremors or shaking, especially when first starting the medication.

4. Palpitations: Some individuals may experience an increased heart rate or palpitations due to the bronchodilator effect of Formoterol.

5. Headache: Mild headaches are a common side effect that can occur with the use of this medication.

Serious Side Effects:

1. Paradoxical Bronchospasm: In rare cases, inhaled medications can cause paradoxical bronchospasm, where the airways constrict instead of dilate, leading to worsening symptoms. If this occurs, the medication should be discontinued immediately, and medical attention should be sought.

2. Adrenal Suppression: Long-term use of corticosteroids can lead to adrenal suppression, where the body’s natural production of corticosteroids is reduced. This is more likely with high doses or prolonged use.

3. Osteoporosis: Prolonged use of corticosteroids can lead to a decrease in bone density, increasing the risk of fractures.

4. Hyperglycemia: Corticosteroids can increase blood sugar levels, which may be of concern for patients with diabetes.

Warnings

There are several important warnings and precautions to consider when using Formoterol Fumarate and Budesonide Inhalation:

1. Not for Acute Symptoms: This medication is not intended for the relief of acute asthma attacks or sudden COPD symptoms. A rescue inhaler (e.g., albuterol) should be used for immediate symptom relief.

2. Risk of Asthma-Related Death: LABAs, such as Formoterol, have been associated with an increased risk of asthma-related death when used alone. Therefore, Formoterol should always be used in combination with an inhaled corticosteroid like Budesonide in asthma patients.

3. Hypersensitivity Reactions: Patients with a known hypersensitivity to Formoterol, Budesonide, or any other components of the inhaler should not use this medication. Symptoms of an allergic reaction can include a rash, itching, swelling, and respiratory distress such as difficulty in breathing.

4. Growth Suppression in Children: Corticosteroids can potentially slow growth in children and adolescents. Use the lowest effective dose and regularly monitor growth to ensure safe and effective treatment.

5. Interactions with Other Medications: Patients should inform their healthcare provider about all medications they are taking, as Formoterol and Budesonide may interact with other drugs, including beta-blockers, diuretics, and certain antifungal and antiviral medications.

• Formoterol Fumarate and Budesonide Inhaler 400 mcg